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"Novel Cell Lysis Solution: Scaling up viral vector harvest with ease and regulatory compliance"

Compliance Without Complexity -- Easy-to-Use Lysis for Scalable Viral Vector Workflows

The rapid rise of gene therapy using AAV and LV vectors has created urgent demand for scalable, high-performance bioproduction. A major challenge is cell lysis—where simplicity, compliance, and efficiency must align. With Triton™ X-100 under EU REACH restriction, a next-gen solution is needed. This white paper explores how J.T.Baker® Cell Lysis Solution (CLS) meets critical criteria: ease of use, regulatory compliance, and process performance. With low viscosity, a concentrated format, and endonuclease compatibility, CLS enables efficient lysis and streamlined downstream processing. Data show CLS matches or outperforms Triton X-100 and polysorbate 20 in yield, particle integrity, and clearance.

Download the white paper to learn how CLS delivers compliant, scalable cell lysis for viral vector production.

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